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Although the clinical features of SARS-CoV-2 infection were first reported in 2019, it has also been established that hospitalized patients with COVID-19, especially those admitted to intensive care unit (ICU), have an increased risk for venous thromboembolism (VTE) despite prophylactic dose anticoagulation.1-4 As a result, some experts have suggested that higher anticoagulation targets may be
Infection with the Alpha (B117) SARS-CoV-2 variant may pose a heightened risk of poor COVID-19 outcomes, according to two observational studies from England and Denmark published yesterday in The Lancet Infectious Diseases. 65% higher odds of death in primary care group In the first study, a team led by University of Oxford researchers studied data on
Turkish hospital study shows benefits of antifungal stewardship Implementing daily, pharmacist-driven antifungal stewardship activities at a tertiary care hospital in Turkey was associated with significant improvements in the appropriateness of antifungal therapy, Turkish researchers reported yesterday in Antimicrobial Agents and Chemotherapy. The researchers evaluated and compared antifungal therapy at the hospital during three different periods.
Vaccine hesitancy and the more transmissible Delta (B1617.2) SARS-CoV-2 variant are fueling a third surge in COVID activity in Russia, with Moscow as the main hot spot. And at a World Health Organization (WHO) briefing today, its Director-General Tedros Adhanom Ghebreyesus, PhD, warned that every world region has countries that are now facing steep increases
CDC looking into TB outbreak in spinal surgery patients The Centers for Disease Control and Prevention (CDC) said this week that it’s investigating a cluster of tuberculosis (TB) infections in patients who’ve recently undergone spinal surgery that used a single lot of a bone repair product. The CDC said patients who underwent spinal fusions or
Outpatient antibiotic durations frequently longer than needed, study finds Nearly 40% of outpatient antibiotic prescriptions in an integrated healthcare system in Denver were longer than necessary, researchers reported yesterday in Open Forum Infectious Diseases. The analysis of antibiotic prescribing across the ambulatory care network of Denver Health from July 2018 to June 2019 looked at
Korean study details risk factors for drug-resistant organisms in COVID patients Multidrug-resistant organisms (MDROs) were isolated in more than a quarter of South Korean patients with confirmed COVID-19 pneumonia and microbial culture results, with corticosteroid use identified as a significant risk factor, researchers reported yesterday in the American Journal of Infection Control. The researchers from
Health experts across the country agree: we are in the midst of a mental health pandemic and have good reason to believe that this mental health crisis will lead to increased cases of depression1 throughout the year. This debilitating illness currently impacts more than 17.3 million American adults, with research2 showing rates have tripled as
Deaths rose 17% in US assisted living residents during COVID-19 From January to August 2020, 17% more US assisted living residents died compared with the same months in 2019, and excess deaths hit 24% in the hardest-hit states, according to a JAMA Network Open research letter yesterday. The researchers used Centers for Medicare & Medicaid
In the year since the global COVID-19 pandemic was declared in March 2020 by the World Health Organization,1 short-term treatments such as prone positioning of patients2 or the use of neutralizing antibody cocktails3 have been optimized, and strategies for patients who remain symptomatic for months or experience long-term sequelae4,5 are being developed. Although several effective
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