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Stewardship / Resistance Scan for Apr 30, 2021

PhRMA report highlights challenges to antibiotic development A new report from the pharmaceutical industry shows there are nearly 90 drugs in clinical development against drug-resistant infections—not nearly enough to meet the growing challenge of antimicrobial resistance (AMR). The report from the Pharmaceutical Research and Manufacturers of America (PhRMA) profiles the 89 drugs from US-based companies

News Scan for Apr 28, 2021

COVID-related inflammatory syndrome hits poorer, minority kids harder Multisystem inflammatory syndrome in children (MIS-C), which has been linked with pediatric COVID-19, may pose higher risks to children in lower socioeconomic statuses or who are minorities, according to a Pediatrics study today. The study compared MIS-C patients with those who had COVID-19, those who were evaluated

Venous Thromboembolism Management in Patients With COVID-19

The severe systemic inflammatory processes and hypercoagulability occurring with COVID-19 illness increase the risk for atherosclerotic plaque disruption and acute myocardial infarction (AMI). Patients with a previous history of coronary disease and/or other significant comorbidities are particularly predisposed to cardiovascular complications with COVID-19 infection.1 In this installment, we will discuss a patient with COVID-19 and

COVID-19 Scan for Apr 27, 2021

Shift work may increase risk of COVID-19 People who work irregular or permanent shifts were associated with double the risk of COVID-19, according to findings from a Thorax study published yesterday. The study looked at 27,056 irregular and 21,836 permanent shift workers between ages 40 to 69, as well as 235,135 non-shift workers, all identified

Potential Drug Interaction Between Warfarin, COVID-19 Treatment Reported

A probable drug interaction was observed in 2 patients taking warfarin who were initiated on remdesivir and dexamethasone for the treatment of COVID-19, according to a case series recently published in the Journal of Pharmacy Practice. The patients, a 71-year-old man and a 62 year-old-man, both on long-term warfarin therapy, presented to the emergency department

COVID-19 Scan for Apr 26, 2021

Higher stroke risk linked to asymptomatic COVID-19 in younger men Men under 50 recovering from asymptomatic COVID have double the likelihood of acute ischemic strokes (AIS) compared with men of the same age without COVID infection, according to a study last week in JAMA Network Open. Eighteen South Asian men were treated in Singapore for

Can you mix COVID-19 vaccines?

Medical News Bulletin – Daily Medical News, Health News, Clinical Trials And Clinical Research, Medical Technology, Fitness And Nutrition News–In One Place There are many vaccines currently in development against COVID-19, and multiple currently being rolled out in countries worldwide. With the demand significantly outpacing supply, some are beginning to wonder whether mixing first and

News Scan for Apr 23, 2021

Phase 2 trial shows high efficacy for malaria vaccine candidate The results of a phase 2b clinical trial indicate 77% efficacy over 12 months of follow-up for a vaccine that targets malaria caused by Plasmodium falciparum, according to a preprint study published this week in The Lancet. The low-dose circumsporozite protein-based vaccine (R21) developed by

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